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el Diputado del Común
coco-espirilo anaerobio
This question was closed without grading. Reason: Other
Jun 10, 2010 19:54
13 yrs ago
1 viewer *
Spanish term

granuloma parasitario de Koch

Spanish to English Other Medical (general)
La tuberculosis en cabeza y cuello:
A) Es una enfermedad con típico "granuloma parasitario de Koch".
B) En la actualidad, aparece con más frecuencia en pacientes inmunodeprinidos.
C) ...

This is from a multiple choice test.
Thanks.
Proposed translations (English)
4 +1 Koch's parasitic granuloma
4 parasitic granuloma induced by/caused by Koch's bacilli/myobacterium tuberculosis

Discussion

Muriel Vasconcellos Jun 12, 2010:
My point was... ...that thre is such a thing as a granuloma, but it's rare.
margaret caulfield Jun 12, 2010:
@Muriel: I truly hope your husband's better now and I really mean that.

However, I feel that we are only here to help with a TRANSLATION. Perhaps on some other forum it would be more appropriate to discuss/explain what this illness, or any other, is all about. Kind regards, Muriel, and I meant what I said!
Muriel Vasconcellos Jun 12, 2010:
Note the quote below My husband developed a granuloma under the conditions described below (http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis):
Mycobacterium outbreaks are often caused by hypervirulent strains of M. tuberculosis. In laboratory experiments, these clinical isolates elicit unusual immunopathology and may be either hyperinflammatory or hypoinflammatory. Studies have shown that the majority of hypervirulent mutants have deletions in their cell wall modifying enzymes or regulators that respond to environmental stimuli. Studies of these mutants have indicated the mechanisms that enable M. tuberculosis to mask its full pathogenic potential, inducing a granuloma that provides a protective niche and enables the bacilli to sustain a long-term persistent infection.
liz askew Jun 11, 2010:
But, hey, what do I know about medical translation? not much obviously.
liz askew Jun 11, 2010:
Medical translation is about understanding the terms, not just blindly translating what is in front of us.
margaret caulfield Jun 11, 2010:
Thanks, Dave. Thanks for your clarification, Dave, although I'm sure most of us understood this to be the case. However, I'm sure we've all learned anything we didn't already know about granulomas!
Dave Pugh (asker) Jun 11, 2010:
Sorry if I wasn't clear. Only the translation of the words highlighted. Not the answer to the question.
liz askew Jun 11, 2010:
#
Granuloma formation and dissemination of Mycobacterium ...
by AGMAS Microbiol - 1999
Granuloma formation and dissemination of Mycobacterium tuberculosis: a novel role for B cells. Bosio CM, Elkins KL; American Society for Microbiology. ...
gateway.nlm.nih.gov/MeetingAbstracts/102195824.html - Cached - Similar
#
NEJM -- The Granuloma in Tuberculosis -- Friend or Foe?
by EJ Rubin - 2009 - Cited by 5 - Related articles
4 Jun 2009 ... On the one hand, activated macrophages are capable of killing or at least controlling the growth of M. tuberculosis. Granulomas are present ...
content.nejm.org/cgi/content/full/360/23/2471 - Similar
margaret caulfield Jun 10, 2010:
Until a short time ago, that was also my impression. Hence, my answer.
Richard McDorman Jun 10, 2010:
From what he wrote, my understanding is that Dave just wants a translation of the term in question. I think that it is very common on multiple-choice tests for many of the wrong answer choices to be made-up pseudo-entities that sound reasonable to an unprepared test-taker.

For support for my contention that (B) is the correct answer (which I admit is a tangential issue here), see http://www.aafp.org/afp/980415ap/moazzez.html.
margaret caulfield Jun 10, 2010:
Well, perhaps Dave should clarify if he wants us to offer the right answer, or if he wants the translation of the question! If it's the latter, I think he should try another non-translation forum.
Richard McDorman Jun 10, 2010:
granuloma parasitario de Koch I believe that the fact that this term cannot be found in any reference material or source whatsoever in Spanish (or English) is a key clue to how it should be translated in English. There is no such thing as "granuloma parasitario de Koch" (in English or Spanish; try Googling the phrase in both languages). I think that this is the point. This is an answer choice in a multiple-choice test, and it is obvious that the correct answer is not (A); it is probably (B).

Tuberculosis, which is the subject of the question, is also (less commonly) known as "Koch's disease" because a common form of tuberculosis is caused by "Koch's bacillus" (see http://www.encyclopedia.com/doc/1O62-Mycobacterium.html).

My best guess would be that the examiner is using that fact, which was perhaps presented in a class lecture or in the course reading, to confuse the unprepared test-taker with an answer choice that, on a superficial level, sounds plausible because it relies on terms that are somewhat familiar to the examinee.

Proposed translations

+1
7 mins

Koch's parasitic granuloma

Declined
Pls see:

11 Drug-induced and toxic granulomatous hepatitis - Elsevier
by KG Ishak - 1988 - Related articles
Parasitic granulomas, such as those due to visceral larva migrans or ... are cholangitisasseen with allopurinol(Koch et al, 1984; Swank et al, 1978), ...
linkinghub.elsevier.com/retrieve/pii/0950352888900127

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Note added at 10 mins (2010-06-10 20:05:02 GMT)
--------------------------------------------------

Gastroenterology
by V Godot - Cited by 15 - Related articles
Parasite Immunol. 1996;18:1–10. MEDLINE. Bresson-Hadni S, Koch S, ... mRNA in parasitic granulomatous disease of the liver, alveolar echinococcosis. ...
www.gastrojournal.org/article/S0016-5085(03)00273-7/referen...

Oral-pharyngeal histoplasmosis
by M Sooknundun - 2007 - Cited by 5 - Related articles
Substitution of anti-Koch's therapy by ..... W. F. and CARDEN, G. A. (1982) Fungal and Parasitic granulomas of the head and neck. ...
journals.cambridge.org/production/action/cjoGetFulltext?fulltextid

Peer comment(s):
agree Richard McDorman : I want to rephrase my comment: I believe that this answer is correct because it correctly conveys the ST meaning. I believe that it is the ST meaning itself that is nonsensical, because this is an answer choice designed to confuse/throw off a test-taker.
26 mins
Thanks, Richard. Again I agree with what you're saying, but let's face it: we're here to help with a translation and not to give lessons or even opinions on whether the writer of the original text is right or wrong about his/her theory/question.
agree Emma Goldsmith : Yes, "parasitic granuloma" and here it is apparently related to Koch.
46 mins
Thanks, Emma. I see you've read my references.
disagree liz askew : 1. Koch does not refer to the man but to Koch's bacilli/myobacterium tuberculosis. 2. It has to make sense to an English reader. My reference showed that Koch's bacteria/m. tub. influences head and neck tuberculosis.
55 mins
I don't see what you're link has to do with Koch, whom I did not invent, so I don't think my answer warrants a "disagree". Pls see my reply to Richard plus my references above. We're suppose to translate the asker's question, whether it's right or wrong.
Something went wrong...
49 mins

parasitic granuloma induced by/caused by Koch's bacilli/myobacterium tuberculosis

Declined
Tuberculosis
- [ Translate this page ]
Enfermedad infectocontagiosa granulomatosa crónica causada por Mycobacterium tuberculosis (bacilo de Koch). Características importantes del Bacilo de Koch ...
www.scribd.com/doc/7218723/Tuberculosis - Cached - Similar

pulmonary granulomas expression of T helper cell 1-type alters the ...
by NW Lukacs - 1997 - Cited by 40 - Related articles
parasite-induced granulomas (I, 2). The exact participation of ..... gen-induced pulmonary granuloma formation production of Th I and Th2 cyto- ...
www.jimmunol.org/cgi/reprint/158/9/4478.pdf
http://webcache.googleusercontent.com/search?q=cache:eUK_JWD...


Tuberculosis is caused by a group of five closely related species, which form the Mycobacterium tuberculosis complex—M. tuberculosis, M. bovis, M. africanum, M. microti, and M. canettii. M. tuberculosis (Koch's bacillus) is responsible for the vast majority of TB cases in the United States. The main defining characteristic of the genus Mycobacterium is the property called “acid-fastness,” which is the ability to withstand decolorization with an acid-alcohol mixture after staining with carbolfuchsin or auramine-rhodamine. Mycobacteria are primarily intracellular pathogens, have slow growth rates, are obligate aerobes, and produce a granulomatous reaction in normal hosts. In cultures, M. tuberculosis does not produce significant amounts of pigment, has a buff-colored, smooth surface appearance, and biochemically produces niacin. These characteristics are useful in differentiating M. tuberculosis from nontuberculous mycobacteria. One characteristic but not distinctive morphologic property of M. tuberculosis is the tendency to form cords, or dense clusters of bacilli, aligned in parallel (Fig. 2). The biochemical background of cording is called cord factor (a trehalose dimycolate), and its contribution to bacterial virulence is still unclear.





--------------------------------------------------
Note added at 52 mins (2010-06-10 20:47:18 GMT)
--------------------------------------------------

Tuberculosis
- [ Translate this page ]
13 May 2010 ... Si las defensas no pueden mantener al bacilo de Koch bajo control, ... Con confirmación histopatológica: (Presencia de granuloma de tipo ... es una enfermedad causada por la larva del parásito llamado tenia solitaria. ...
www.icn.minsa.gob.pe/index.php?option=com_content... - Cached

--------------------------------------------------
Note added at 55 mins (2010-06-10 20:50:14 GMT)
--------------------------------------------------

Tuberculosis
Bacterium. Tuberculosis is caused by the infectious agent known as Mycobacterium tuberculosis (Mtb). This rod-shaped bacterium, also called Koch's bacillus, ...
my.clevelandclinic.org/.../tuberculosis/hic_tuberculosis_2.aspx - Cached - Similar
Peer comment(s):
margaret caulfield : I don't see what you're link has to do with Koch, whom I did not invent, so I don't think my answer warrants a "disagree". Pls see my reply to Richard plus my references above. We're suppose to translate the asker's question, whether it's right or wrong.
32 mins
Koch is the bacillus = myobacterium tuberculosis, nothing to do with the bloke as such.
Something went wrong...
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